A randomized trial of rescue angioplasty versus a conservative approach for failed fibrinolysis in ST-segment elevation myocardial infarction
نویسنده
چکیده
ndrew G. C. Sutton, MA, MB, MRCP,* Philip G. Campbell, MB, MRCP,* ichard Graham, MB, MRCP,* Dallas J. A. Price, MB, MRCP,* Janine C. Gray, BSC(HONS), PHD,† ver D. Grech, MD, MRCP, FACC,* James A. Hall, MA, MD, FRCP,* lun A. Harcombe, MD, MRCP,* Robert A. Wright, MD, FRCP,* oger H. Smith, BSC(HONS), MB, FRCP,‡ Jerry J. Murphy, MB, BS, DM, FRCP,§ nanthaiah Shyam-Sundar, MB, BS, MD, DM, FRCP,‡ Michael J. Stewart, MD, FRCP,* drian Davies, BSC, MB, BS, FRCP,* Nicholas J. Linker, BSC, MD, FRCP, FESC,* ark A. de Belder, MA, MD, FRCP* iddlesbrough, Newcastle-upon-Tyne, Stockton-on-Tees, and Darlington, United Kingdom
منابع مشابه
Rescue angioplasty or repeat fibrinolysis after failed fibrinolytic therapy for ST-segment myocardial infarction: a meta-analysis of randomized trials.
OBJECTIVES We sought to best estimate the benefits and risks associated with rescue percutaneous coronary intervention (PCI) and repeat fibrinolytic therapy as compared with conservative management in patients with failed fibrinolytic therapy for ST-segment myocardial infarction (STEMI). BACKGROUND Fibrinolytic therapy is the most common treatment for STEMI; however, the best therapy in patie...
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متن کاملValue of first day angiography/angioplasty in evolving Non-ST segment elevation myocardial infarction: an open multicenter randomized trial. The VINO Study.
AIMS Direct angioplasty is an effective treatment for ST-elevation myocardial infarction. The role of very early angioplasty in non-ST-elevation infarction is not known. Thus, a randomized study of first day angiography/angioplasty vs early conservative therapy of evolving myocardial infarction without persistent ST-elevation was conducted. METHODS One hundred and thirty-one patients with con...
متن کاملPrimary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trial.
AIMS In patients with acute myocardial infarction and ST-segment elevation (STEMI), primary angioplasty is frequently not available or performed beyond the recommended time limit. We designed a non-inferiority, randomized, controlled study to evaluate whether lytic-based early routine angioplasty represents a reasonable reperfusion option for victims of STEMI irrespective of geographic or logis...
متن کاملInterventional Cardiology Primary Angioplasty Versus Fibrinolysis in Acute Myocardial Infarction Long-Term Follow-Up in the Danish Acute Myocardial Infarction 2 Trial
Background—The Danish Acute Myocardial Infarction 2 (DANAMI-2) study found that primary angioplasty (primary percutaneous coronary intervention [pPCI]) compared with fibrinolysis reduced 30-day adverse events in patients with ST-segment elevation myocardial infarction. The present study investigated whether the benefit of pPCI was maintained at a long-term follow-up. Methods and Results—We rand...
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